Everybody seems to want to make the back of their vehicle into a mini room like in a house, but I've gone the other way with my Honda Odyssey minivan and made mine into a sleeping pod area, tent-like, especially for the winter. Think "covered wagon" with 3 ten foot 1/2 inch pvc pipes bent on the inside and held in place mostly by the sides and roof. The first one is behind the front seats, the second in the middle, and the 3rd in front of where the rear back seat had been.
This provides a frame for an 8'x10' emergency blanket tarp to be pulled over the top to reflect any heat back towards me. Since the length of my space is 6', I use the 8' length from back to front so there's a foot of tarp that hangs over the front and back while the 12' length completely covers the side windows for privacy. I can also use black-out curtains threaded through the front and back pvc hoops to provide privacy where no light can be seen escaping the back of the van.
I am in Wisconsin and for moderate cold near freezing it is just fine and comfortable with a good winter sleeping bag. I also have a solar battery that will run a heating pad all night and when placed over my chest section keeps me nice and warm. But I also have a Buddy Portable that I have used--running for under an hour at a time until it gets warm, then in the night when I wake up and it's too cold I'll turn it back on for awhile again.
The back of my van is in no way air tight and I can feel cool air moving enough that I'm not worried about carbon monoxide when the heater is running. There is condensation on the front window and the side with the heater, but I just wipe it down in the morning.
The beauty is that other than the pvc hoops, which are not a big deal, can be taken down and put away after the night. In fact, in a half hour I can have the entire back of my van emptied out with nothing in it. But it's a sleeping pod, like a winter tent, and not meant to be a room or like an RV.