Hi! Thought this would be a great place to make my first post!!
This was my first year since going on the road that I spent months of time in mountains during winter. I was in Utah, Oregon, and Washington State. No where near the temps (-40) your talking about however. This timing also conincided with a setup change that I've been researching for about a year.
I started out wintering in a Black Series trailer. These trailers have no floor insulation and the entire water system is exposed. My unit also had a cassette toilet. I ran the water system dry, meaning nothing in the tanks with all the lines and the water heater blown out. I just used water jerries and added RV anti-freeze into the grey tank. The cassette was inside the heated compartment, so it didn't freeze. You could also add RV anti-freeze to the cassette. At this point temps ranged from about 10f to 33f. Trailer had a single Dometic 10k heater and it ran constantly. I burned through a 30Lb propane tank about every 7 days. The biggest issues are condensation. You have to keep air flowing through not only the main cabin, but also all of your compartments. Closed lockers will pool condensation soaking everything inside and will freeze the condensate on exterior walls in campers/trailers/vans that have thermal bridges.
About half way through this year's mountain time I moved into a Northern Lite truck camper. The cold weather difference is amazing. NL and Bigfoot make a mountain superstar. Being insulated fully AND not suffering from the problems associated with thermal bridges usually found in aluminum framed campers, they hold heat very well and allow you to use drastically less fuel for heating. They also take into consideration the problems of operating in the cold. Each locker is vented, the windows are thermal pane, the dump valves are located in a heated compartment, and the basement is heated as are the tanks.
As for heaters, I'm not a fan of the forced air propane type. They get super finicky and fail quite often (at least mine have). I've had two brand new Dometic heaters fail, mostly related to air flow through the system and high altitude. I'm a HUGE fan of Planar Forced air diesel heaters. They're simple to work on in the field and very reliable as compared to what comes in most campers. I've also had to rely on catalytic heaters for extended periods. They're fine in dry environments, but even vented become a huge liability when there's snow outside.
If I was starting from scratch, I'd take some time and hunt down a used BigFoot 2500. I think that would be the absolute best bet for Alaska. The only major issue is that your probably gonna want a 1 ton dually. They are big campers.