Yes I'm OK with this setup wrt safety issues, as long as there are working alarms and the box is well sealed and vented outside.
Space is the big problem, cold weather may use well over a gallon a day, and I want to be able to remote boondock a couple of weeks, going back in for food rather than fuel, so ideally we'll be able to carry ~100# or so.
OT but yes I have lived with propane fridges & lighting, in fact for several years completely off grid in the outback. But I agree, these days a decent solar/battery setup and proper compressor fridge is the way to go, albeit a pricey one.
Maybe do both? in which case use the compressor box just to freeze the meat and make ice for coolers, max flexibility plus belt & suspenders redundancy.