Well it's not a van, but I have 389,000 miles on my 06 Chevy Cobalt SS I use to pull my Aliner (65,000+ miles towing).
To be fair, I just replaced the engine at 385,000 miles and the used transmission I put in it is making a little noise and will need replacing soon, but I plan on doing so, as I will be keeping it till I die. (Repairs are cheaper than car notes and the full coverage insurance I'd be forced to get.)
Chip