Hey Curtis - hope this helps:
I have a '99 E350 extended cargo. Triton V10, has an aux transmission cooler & now a (used) trailer hitch. My neighbor & I recently went bumper to bumper (pretty much) ensuring it's road ready when I finish up the projects. I mostly watched while he was explaining everything, but did help. He changed the sparkplugs without much problem other than he's a size lrg & the space was cramped - next, I'm gonna change out the sensors while he supervises. We dismounted the transmission & took it in to have the U joint mounted & dismounted & took the the ball joints in. The water pump was a real pain, but it was original & I figured it better to have all that kinda stuff new, brakes, rotors & repacked the wheel bearings. (ok so I'm an older female & wanted someone to hold my hand since I don't have much experience mechanically speaking & TRULY prefer not to break down). The alternator & starter had already been replaced a month or so b4 I bought it, tranny 2 yrs ago.
So far I like the ford, although I still haven't gotten the differential oil smell outa my jeans. Since it's basically a commercial vehicle, it should be durable since the maintenance was kept up by the previous owner & figure I can keep up with it . I acquired the 2 shop manuals for it & bought a Haynes as well.