One of the reasons to seal plywood is not for rotting, even with the worst condensation you won't get plywood to rot in the van.
But with CDX you might get delamination and if you have any leaks, you will get water staining.
I treat my van build like a boat build.
All 6 sides (yes 6, top, bottom, left, right, front and back) of every piece of wood is sealed with either clear polyurethane or Durabak brush-on bedliner. This includes wooden stringers and ply that are treated on all sides BEFORE assembly.
The fewer absorbent surfaces in any build that will hold moisture, the better off you are.
It's the same reason I don't use any batting type insulation (fiberglass, hollowfill, thinsulate).
While those things won't technical absorb water at the individual fiber level like cotton, the dense batting will trap moisture. Especially paperfaced insulation.
Eliminating absorbent surfaces in a build is important.
If things do get wet/dewy you can dry the interior quicker if water isn't absorbed by anything.
At the minimum, paint every wood surface to help seal it. Ideally oil-based.
One plus is if you paint the interiors of cabinets and bins, a light/bright color, it makes things easier to find.