yes, most defiantly yes!
i have been using residential panels on my rigs exclusively for years. for me, they are the best bang for the buck and quite often the easiest way to get the most power from a small roof
right now i have a single 435 watt sunpower panel on my minivan. previously i had 2x 235 watt canadian solar panels on the same minivan for over 2 years and 50,000 miles of cross country travel with tons of boonedocking and forest service roads and logging roads.
i also have 6x 295 watt REC residential panels on my short bus, 4 on the roof and 2 on tilt up mounts down the side. i have taken this everyware from the the canadian border to quartzsite. dirt roads and highways.
i have installed or helped others with using these type panels on many other rigs and have not had any problems.
most residential panels are rated for very high winds, like hurricane force. also they are rated for snow loads often exceeding 100# per square foot. the glass is tempered and most can withstand golfball sized hail
i have had zero issues or problems with my residential panels.
just make sure your mounts are just as secure. driving down the interstate is almost like sitting through a hurricane
as jim said, you do need to make sure all the rest of the system is proper
but yes, the panels can be safely mounted and used on mobile rigs