Most remote areas

[Kaylee]

Wayne wins the internet (bolding added by me):

Places very hard to reach would keep most of humanity away. Most like to park close to the storefront.
Places with climate extremes. Hot days and frigid nights.
Places that are not "destinations".

CatCaretaker:
You often do not need to go thousands of miles, particularly if you're just looking for a respite/noise-detox for a week or so.
The key is to find a relatively isolated large area, then go just beyond the popular spots.

Specifically:
Get the (free) "Motor Vehicle Use Map" (aka MVUM) for your nearest National Forest (Chattahoochee-Oconee??).
Use the internet and the map to find the less popular designated campgrounds. Now use the map to check out the roads nearby. If there's one that goes beyond the campground, but does not go anywhere "interesting", it's an excellent candidate for quiet dispersed camping.
Optional: cross reference with GoogleMaps' satellite view (mainly to look for houses - many NFs have large areas of housing, but they're usually at the edges & waterways, along very good roads).
Even a mere half mile further down a dead end type road, can be awesome. A couple of miles, can be even more awesome.

I stumbled upon this approach, largely by accident, and it's worked well for me in three NFs (Mark Twain in MO, Ottawa in MI, and Chequamegon-Nicolet in WI).
My quietest spot (so far), was right beside a gravel/dirt logging style road. Had about one vehicle per day drive past, and they never stopped. I was on the "main"-ish road, two miles past a no-fee designated campground.

For me (Traumatic Brain Injury survivor), Quiet isn't a "want" it's a "need", and I do understand you/anybody's quest for it.
Good luck! You can find Quiet. Just take it in small steps.

 

[jimindenver]

The Rocky Mountains.

 

[WanderingRose]

Northern Minnesota and the Upper Peninsula of Michigan are two of my favorite areas, both remarkably sparsely populated and heavily treed.

Remote can be found.

There are busy and less busy federal campgrounds, plus other public and private campgrounds of all sorts, but you’re never a very long drive away from essential services.

For we midwesterners, it is much cooler up there in the summer than it is here, and Lake Superior is especially beautiful.

 

[RoamerRV428]

if I wanted remote and away from humanity, are we talking totally or not cause I would just hit an out of the way state park and just live. 2 weeks or so you can move to another state park just as remote probably. I could state park my way thru my life HAHA I mean I have been to a ton of state parks on the east coast and I have hit quite a few that have like no one in them.….I can hole up and see almost no one, don't drive out into public unless needed and I can make myself very remote…..heck some state campgrounds in like TN and AL and AR are like in the middle of nowhere...so in honesty I can 'remote' myself kinda easily.